Good thread indeed! Checked out the Nonoba site and downloaded the API, I haven't looked at it yet, but i get the impression that the Api will only work on the nonoba.com website? I can't be sure, but it seems like one of those kind of deals, ya know?
I'm comparing performance at this point and I'm just about to lower my expectations overall. I need to test on different machines and I have a lot more to research to do still, but my impression is I may have to steer away from using something like this with twichy action games and think more in terms of strategy or RPGs.